MolNFT v1 · #142823 · protein

Structure of RAC1 in the low-affinity state for MG2+

6AGP · RAS-related C3 botulinum toxin substrate 1: “Structure of RAC1 in the low-affinity state for MG2+”. Solution nmr, 2 ligands (GDP, MG), 1 pocket (best druggability 0.52). MolNFT v1 #142823 on GenesisL1: 3D structure, binding sites…

PDB: 6AGP
Type: protein
Length: 181 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RAS-related C3 botulinum toxin substrate 1
UniProt: P63000
Ligands: GDP, MG
Pockets: 1 · best druggability 0.52

Structure

solution nmr · 1 distinct chain · 40% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAS-related C3 botulinum toxin substrate 1	protein	181	40% helix, 22% strand	P63000

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	143	0.52	0.79	19	empty

Compared structures

6AGP · Structure of Rac1 in the low-affinity state for Mg2+ · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P63000
Elsewhere: RCSB PDB 6AGP · PDBe 6AGP · UniProt P63000

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