MolNFT v1 · #142428 · protein
R1EN(5-227)-ubiquitin fusion
6A44 · RNA-directed DNA polymerase homolog (R1),POLYUBIQUITIN-C: “R1EN(5-227)-ubiquitin fusion”. X-ray diffraction, 2 pockets (best druggability 0.62). MolNFT v1 #142428 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6A44
- Type
- protein
- Length
- 294 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA-directed DNA polymerase homolog (R1),POLYUBIQUITIN-C
- EC
- 2.7.7.49
- UniProt
- Q7M4J4, P0CG48
- Pockets
- 2 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 23% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA-directed DNA polymerase homolog (R1),POLYUBIQUITIN-C (EC 2.7.7.49) | protein | 294 | 23% helix, 32% strand | Q7M4J4, P0CG48 |
Ligands and binding sites
- ACY · Acetic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 410 | 0.62 | 0.77 | 32 | empty |
| 2 | 119 | 0.38 | 0.74 | 24 | empty |
Compared structures
- 6A44 · R1EN(5-227)-ubiquitin fusion · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7M4J4
- Every structure of UniProt P0CG48
- Elsewhere: RCSB PDB 6A44 · PDBe 6A44 · UniProt Q7M4J4 · UniProt P0CG48
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