MolNFT v1 · #141036 · protein

Crystal structure of voltage-gated sodium channel navab E32Q mutant

5YUB · Ion transport protein: “Crystal structure of voltage-gated sodium channel navab E32Q mutant”. X-ray diffraction, 2 ligands (1N7, CA), 2 pockets (best druggability 0.44). MolNFT v1 #141036 on GenesisL1: 3D structure, binding sites…

PDB: 5YUB
Type: protein
Length: 229 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ion transport protein
UniProt: A0A239WB15
Ligands: 1N7, CA
Pockets: 2 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 84% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ion transport protein	protein	229	84% helix, 0% strand	A0A239WB15

Ligands and binding sites

1N7 · Chapso · ligand · chains A
CA · Calcium ion · metal
LMT · Dodecyl-beta-D-maltoside · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	118	0.44	0.78	18	empty
2	85	0.37	0.76	16	empty

Compared structures

5YUB · Crystal structure of voltage-gated sodium channel NavAb E32Q mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A239WB15
Elsewhere: RCSB PDB 5YUB · PDBe 5YUB · UniProt A0A239WB15

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.