MolNFT v1 · #140142 · protein

Crystal structure of daxx helical bundle domain in complex with atrx

5Y18 · Death domain-associated protein 6: “Crystal structure of daxx helical bundle domain in complex with atrx”. X-ray diffraction. MolNFT v1 #140142 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5Y18
Type: protein
Length: 102 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Death domain-associated protein 6; Transcriptional regulator atrx
EC: 3.6.4.12
UniProt: Q9UER7, P46100

Structure

x-ray diffraction · 2 distinct chains · 79% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Death domain-associated protein 6	protein	85	78% helix, 2% strand	Q9UER7
B	Transcriptional regulator atrx (EC 3.6.4.12)	protein	17	88% helix, 0% strand	P46100

Interfaces

1 interface between chains.

A–B · 580 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

5Y18 · Crystal structure of DAXX helical bundle domain in complex with ATRX · the same entry in another collection · chain A against A, TM-score 1.00
Q9UER7 · AlphaFold monomer V2.0 prediction for death domain-associated protein 6 (Q9UER7) · a predicted model of the same protein · chain A against A, TM-score 0.94
P46100 · AlphaFold monomer V2.0 prediction for transcriptional regulator atrx (P46100) · a predicted model of the same protein · chain B against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UER7
Every structure of UniProt P46100
Elsewhere: RCSB PDB 5Y18 · PDBe 5Y18 · UniProt Q9UER7 · UniProt P46100

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