MolNFT v1 · #138200 · protein
Crystal structure of the arabidopsis thaliana raptor in complex with the tos peptide of human 4EBP1
5WBJ · Regulatory-associated protein of tor 1: “Crystal structure of the arabidopsis thaliana raptor in complex with the tos peptide of human 4EBP1”. X-ray diffraction, 13 pockets (best druggability 0.85). MolNFT v1 #138200 on GenesisL1…
- PDB
- 5WBJ
- Type
- protein
- Length
- 1,066 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory-associated protein of tor 1; Eukaryotic translation initiation factor…
- UniProt
- Q93YQ1, Q13541
- Pockets
- 13 · best druggability 0.85
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulatory-associated protein of tor 1 | protein | 1058 | 39% helix, 19% strand | Q93YQ1 |
| T | Eukaryotic translation initiation factor 4E-binding protein 1 | protein | 8 | 0% helix, 0% strand | Q13541 |
Pockets
13 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 861 | 0.85 | 0.87 | 73 | empty |
| 2 | 142 | 0.75 | 0.93 | 22 | empty |
| 3 | 316 | 0.64 | 0.80 | 26 | empty |
| 4 | 318 | 0.63 | 0.80 | 31 | empty |
| 5 | 416 | 0.62 | 0.77 | 64 | empty |
Interfaces
1 interface between chains.
- A–T · 685 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 5WBJ · Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of… · the same entry in another collection · chain A against A, TM-score 1.00
- Q93YQ1 · AlphaFold monomer V2.0 prediction for regulatory-associated protein of tor 1 (Q93YQ1) · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q13541 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 4E-binding… · a predicted model of the same protein · chain T against A, TM-score 0.49
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93YQ1
- Every structure of UniProt Q13541
- Elsewhere: RCSB PDB 5WBJ · PDBe 5WBJ · UniProt Q93YQ1 · UniProt Q13541
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