MolNFT v1 · #137239 · protein

Crystal structure of GLUN1/GLUN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-acepc

5VIH: “Crystal structure of GLUN1/GLUN2A NMDA receptor agonist binding domains with glycine and antagonist…”. X-ray diffraction, 1 ligand (5DZ). MolNFT v1 #137239 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5VIH
Type: protein
Length: 548 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P35439, Q00959
Ligands: 5DZ

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	270	—	P35439
B	—	protein	278	—	Q00959

Ligands and binding sites

5DZ · 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid · ligand · chains B
PEG · Di(hydroxyethyl)ether · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5VIH · Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and… · the same entry in another collection · chain B against B, TM-score 1.00
P35439 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 1 (P35439) · a predicted model of the same protein · chain A against A, TM-score 0.97
Q00959 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2A (Q00959) · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35439
Every structure of UniProt Q00959
Elsewhere: RCSB PDB 5VIH · PDBe 5VIH · UniProt P35439 · UniProt Q00959

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.