MolNFT v1 · #136987 · protein
Crystal structure of human prolyl-tRNA synthetase (prs) in complex with inhibitor
5VAD: “Crystal structure of human prolyl-tRNA synthetase (prs) in complex with inhibitor”. X-ray diffraction, 2 ligands (91Y, ZN). MolNFT v1 #136987 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5VAD
- Type
- protein
- Length
- 965 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P07814
- Ligands
- 91Y, ZN
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 482 | — | P07814 |
| B | — | protein | 483 | — | P07814 |
Ligands and binding sites
- 91Y · 3-[(cyclohexanecarbonyl)amino]-N-(2,3-dihydro-1H-inden-2-yl)pyrazine-2-carboxamide · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5VAD · Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor · the same entry in another collection · chain B against B, TM-score 1.00
- P07814 · AlphaFold monomer V2.0 prediction for bifunctional GLUTAMATE/PROLINE --tRNA ligase… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07814
- Elsewhere: RCSB PDB 5VAD · PDBe 5VAD · UniProt P07814
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