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MolNFT v1 · #135397 · protein + DNA

DNA polymerase mu pre-catalytic ground state ternary complex, CA2+

5TXX: “DNA polymerase mu pre-catalytic ground state ternary complex, CA2+”. X-ray diffraction, 3 ligands (TTP, CA, NA). MolNFT v1 #135397 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5TXX
Type
protein + DNA
Length
346 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q9NP87
Ligands
TTP, CA, NA

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein329—Q9NP87
T—dna9——
P—dna4——
D—dna4——

Ligands and binding sites

  • TTP · Thymidine-5'-triphosphate · ligand · chains A, T, P
  • CA · Calcium ion · metal · 2 copies · chains A, P
  • NA · Sodium ion · metal · chains A, P
  • EDO · 1,2-ethanediol · additive · 3 copies · chains A, T, P
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5TXX · DNA Polymerase Mu Pre-Catalytic Ground State Ternary Complex, Ca2+ · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9NP87 · AlphaFold monomer V2.0 prediction for DNA-directed DNA/RNA polymerase mu (Q9NP87) · a predicted model of the same protein · chain A against A, TM-score 0.99

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