MolNFT v1 · #135032 · protein
Crystal structure of the er-alpha ligand-binding domain (Y537S) in complex with the arene core obhs derivative, 4-bromophenyl 4,4''- dihydroxy-[1,1':2',1''-terphenyl]-4'-sulfonate
5TMQ: “Crystal structure of the er-alpha ligand-binding domain (Y537S) in complex with the arene core obhs…”. X-ray diffraction, 1 ligand (7M7). MolNFT v1 #135032 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TMQ
- Type
- protein
- Length
- 496 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P03372, Q15596
- Ligands
- 7M7
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 234 | — | P03372 |
| B | — | protein | 243 | — | P03372 |
| C | — | protein | 9 | — | Q15596 |
| D | — | protein | 10 | — | Q15596 |
Ligands and binding sites
- 7M7 · 4-bromophenyl 4,4''-dihydroxy-[1,1':2',1''-terphenyl]-4'-sulfonate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5TMQ · Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Arene… · the same entry in another collection · chain A against A, TM-score 1.00
- P03372 · AlphaFold monomer V2.0 prediction for estrogen receptor (P03372) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03372
- Every structure of UniProt Q15596
- Elsewhere: RCSB PDB 5TMQ · PDBe 5TMQ · UniProt P03372 · UniProt Q15596
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