MolNFT v1 · #134934 · protein
Structure of WWP2 2,3-linker-hect
5TJQ · NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3…: “Structure of WWP2 2,3-linker-hect”. X-ray diffraction, 2 pockets (best druggability 0.74). MolNFT v1 #134934 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5TJQ
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2
- EC
- 2.3.2.26
- UniProt
- O00308
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NEDD4-like E3 ubiquitin-protein ligase WWP2,NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 2.3.2.26) | protein | 361 | 49% helix, 9% strand | O00308 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 362 | 0.74 | 0.85 | 52 | empty |
| 2 | 173 | 0.68 | 0.87 | 33 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00308
- Elsewhere: RCSB PDB 5TJQ · PDBe 5TJQ · UniProt O00308
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