MolNFT v1 · #129706 · protein

Glic-gabaar ALPHA1 chimera crystallized in complex with thdoc at PH4.5

5OSB: “Glic-gabaar ALPHA1 chimera crystallized in complex with thdoc at PH4.5”. X-ray diffraction, 2 ligands (A8Z, CL). MolNFT v1 #129706 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5OSB
Type: protein
Length: 1,562 residues
Chains: 5
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q7NDN8, P62812
Ligands: A8Z, CL

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, D, E	—	protein	313	—	Q7NDN8, P62812
C	—	protein	310	—	Q7NDN8, P62812

Ligands and binding sites

A8Z · Tetrahydrodeoxycorticosterone · ligand · 5 copies · chains A, E, B, C, D
CL · Chloride ion · ion · 2 copies · chains A, D
ACT · Acetate ion · additive · 5 copies · chains A, E, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5OSB · GLIC-GABAAR alpha1 chimera crystallized in complex with THDOC at pH4.5 · the same entry in another collection · chain A against A, TM-score 1.00
Q7NDN8 · AlphaFold monomer V2.0 prediction for proton-gated ion channel (Q7NDN8) · a predicted model of the same protein · chain A against A, TM-score 0.95
P62812 · AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor subunit alpha-1… · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7NDN8
Every structure of UniProt P62812
Elsewhere: RCSB PDB 5OSB · PDBe 5OSB · UniProt Q7NDN8 · UniProt P62812

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.