MolNFT v1 · #128971 · protein
Human NMT1 in complex with myristoyl-CoA and inhibitor imp-917
5O6H: “Human NMT1 in complex with myristoyl-CoA and inhibitor imp-917”. X-ray diffraction, 4 ligands (MYA, 9M2, MG). MolNFT v1 #128971 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5O6H
- Type
- protein
- Length
- 764 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P30419
- Ligands
- MYA, 9M2, MG, PO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 382 | — | P30419 |
Ligands and binding sites
- MYA · Tetradecanoyl-coa · ligand · 2 copies · chains A, B
- 9M2 · 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine · ligand · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · 8 copies · chains A, B
- GOL · Glycerol · additive · 3 copies · chains A, B
- DMS · Dimethyl sulfoxide · additive
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5O6H · Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-917 · the same entry in another collection · chain A against A, TM-score 1.00
- P30419 · AlphaFold monomer V2.0 prediction for glycylpeptide N-tetradecanoyltransferase 1 (P30419) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30419
- Elsewhere: RCSB PDB 5O6H · PDBe 5O6H · UniProt P30419
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