MolNFT v1 · #128199 · protein
Structure of interleukin 23 in complex with briakinumab Fab
5NJD: “Structure of interleukin 23 in complex with briakinumab Fab”. X-ray diffraction, 4 ligands (NAG, MAN, BMA). MolNFT v1 #128199 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5NJD
- Type
- protein
- Length
- 5,146 residues
- Chains
- 24
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P29460, Q9NPF7
- Ligands
- NAG, MAN, BMA, SO4
Structure
x-ray diffraction · 20 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 298 | — | P29460 |
| B | — | protein | 144 | — | Q9NPF7 |
| C | — | protein | 294 | — | P29460 |
| D | — | protein | 146 | — | Q9NPF7 |
| E | — | protein | 294 | — | P29460 |
| F | — | protein | 146 | — | Q9NPF7 |
| G | — | protein | 293 | — | P29460 |
| H | — | protein | 139 | — | Q9NPF7 |
| I | — | protein | 292 | — | P29460 |
| J | — | protein | 141 | — | Q9NPF7 |
| K | — | protein | 297 | — | P29460 |
| L | — | protein | 139 | — | Q9NPF7 |
| M, O, Q | — | protein | 213 | — | — |
| N, P | — | protein | 207 | — | — |
| R | — | protein | 208 | — | — |
| S, W | — | protein | 214 | — | — |
| T | — | protein | 208 | — | — |
| U | — | protein | 215 | — | — |
| V | — | protein | 205 | — | — |
| X | — | protein | 206 | — | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains A, C, E, G, I, K
- MAN · alpha-D-mannopyranose · sugar · 12 copies
- BMA · beta-D-mannopyranose · sugar · 6 copies
- SO4 · Sulfate ion · ion · 13 copies · chains K, M, N, O, I, P, Q, C, R, S, T, U, V, W, X
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5NJD · Structure of Interleukin 23 in complex with Briakinumab FAb · the same entry in another collection · chain K against K, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29460
- Every structure of UniProt Q9NPF7
- Elsewhere: RCSB PDB 5NJD · PDBe 5NJD · UniProt P29460 · UniProt Q9NPF7
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