MolNFT v1 · #127823 · protein

Structure of RPA70N in complex with primpol (fragment 514-525)

5N85 · Replication protein a 70 kda DNA-binding subunit: “Structure of RPA70N in complex with primpol (fragment 514-525)”. X-ray diffraction. MolNFT v1 #127823 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5N85
Type: protein
Length: 133 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Replication protein a 70 kda DNA-binding subunit; DNA-directed PRIMASE/POLYMERASE protein
EC: 2.7.7.-
UniProt: P27694, Q96LW4

Structure

x-ray diffraction · 2 distinct chains · 20% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Replication protein a 70 kda DNA-binding subunit	protein	121	20% helix, 41% strand	P27694
B	DNA-directed PRIMASE/POLYMERASE protein (EC 2.7.7.-)	protein	12	25% helix, 0% strand	Q96LW4

Interfaces

1 interface between chains.

A–B · 644 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

5N85 · Structure of RPA70N in complex with PrimPol (fragment 514-525) · the same entry in another collection · chain A against A, TM-score 1.00
P27694 · AlphaFold monomer V2.0 prediction for replication protein a 70 kda DNA-binding subunit… · a predicted model of the same protein · chain A against A, TM-score 0.96
Q96LW4 · AlphaFold monomer V2.0 prediction for DNA-directed PRIMASE/POLYMERASE protein (Q96LW4) · a predicted model of the same protein · chain B against A, TM-score 0.45

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27694
Every structure of UniProt Q96LW4
Elsewhere: RCSB PDB 5N85 · PDBe 5N85 · UniProt P27694 · UniProt Q96LW4

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