MolNFT v1 · #127424 · protein

Human JAGGED2 C2-EGF2

5MW5 · Protein jagged-2: “Human JAGGED2 C2-EGF2”. X-ray diffraction, 2 ligands (NAG, CA). MolNFT v1 #127424 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5MW5
Type: protein
Length: 258 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein jagged-2
UniProt: Q9Y219
Ligands: NAG, CA

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein jagged-2	protein	258	1% helix, 41% strand	Q9Y219

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
CA · Calcium ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 12 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

5MW5 · Human Jagged2 C2-EGF2 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y219 · AlphaFold monomer V2.0 prediction for protein jagged-2 (Q9Y219) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y219
Elsewhere: RCSB PDB 5MW5 · PDBe 5MW5 · UniProt Q9Y219

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