UniProt Q9Y219
Protein jagged-2 (Q9Y219)
Protein jagged-2 (UniProt Q9Y219): 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y219
- Protein
- Protein jagged-2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 11 · 1 record with a druggable one
Structures
7 records of Q9Y219 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MW5 | Human Jagged2 C2-EGF2 | x-ray diffraction | A | NAG, CA | — |
| 5MW5 | Human JAGGED2 C2-EGF2 | x-ray diffraction | A | NAG, CA | — |
| 5MW7 | Human Jagged2 C2-EGF3 | x-ray diffraction | A | FUC | — |
| 5MW7 | Human JAGGED2 C2-EGF3 | x-ray diffraction | A | FUC | — |
| 5MWF | Human Jagged2 C2-EGF2 | x-ray diffraction | A, B, C, D, E, F | NAG, FUC, CA, CL | 11 (best 0.73) |
| 5MWF | Human JAGGED2 C2-EGF2 | x-ray diffraction | A, B, C, D, E, F | NAG, FUC, CA, CL | — |
| Q9Y219 | AlphaFold monomer V2.0 prediction for protein jagged-2 (Q9Y219) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5MWF chain F against the predicted model Q9Y219: TM-score 0.95, RMSD 1.43 Å
- 5MWF chain F against the predicted model Q9Y219: TM-score 0.95, RMSD 1.43 Å
- 5MW5 chain A against the predicted model Q9Y219: TM-score 0.93, RMSD 1.73 Å
- 5MW5 chain A against the predicted model Q9Y219: TM-score 0.93, RMSD 1.73 Å
- 5MWF chain D against the predicted model Q9Y219: TM-score 0.92, RMSD 1.93 Å
- 5MWF chain D against the predicted model Q9Y219: TM-score 0.92, RMSD 1.93 Å
- 5MW7 chain A against the predicted model Q9Y219: TM-score 0.87, RMSD 2.84 Å
- 5MW7 chain A against the predicted model Q9Y219: TM-score 0.87, RMSD 2.84 Å
- 5MWF chain C against the predicted model Q9Y219: TM-score 0.83, RMSD 2.70 Å
- 5MWF chain C against the predicted model Q9Y219: TM-score 0.83, RMSD 2.70 Å
Elsewhere
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