MolNFT v1 · #127372 · protein
X-ray structure of the 2-22' locally-closed mutant of glic in complex with propofol
5MUO: “X-ray structure of the 2-22' locally-closed mutant of glic in complex with propofol”. X-ray diffraction, 2 ligands (PFL, CL). MolNFT v1 #127372 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5MUO
- Type
- protein
- Length
- 1,555 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q7NDN8
- Ligands
- PFL, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E | — | protein | 311 | — | Q7NDN8 |
Ligands and binding sites
- PFL · 2,6-bis(1-methylethyl)phenol · ligand · chains A, B, C, D, E
- CL · Chloride ion · ion · 5 copies · chains A, B, C, D, E
- ACT · Acetate ion · additive · 4 copies · chains A, B, D, E
- LMT · Dodecyl-beta-D-maltoside · additive · chains A, B, C, D, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5MUO · X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol · the same entry in another collection · chain E against E, TM-score 1.00
- Q7NDN8 · AlphaFold monomer V2.0 prediction for proton-gated ion channel (Q7NDN8) · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7NDN8
- Elsewhere: RCSB PDB 5MUO · PDBe 5MUO · UniProt Q7NDN8
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