Ligand · PFL
PFL · 2,6-bis(1-methylethyl)phenol
PFL, 2,6-bis(1-methylethyl)phenol (C12 H18 O, 178.3 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…
- Component
- PFL
- Formula
- C12 H18 O
- Class
- ligand
- Structures
- 12
- PDB entries
- 7
Binding sites
PFL in 12 structures; the first of them:
- 5MUO · X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol · PFL D402 · binds THR226, SER230, THR226, SER230, THR226, SER230, ILE233, THR226 and 4 more
- 5MUR · X-ray structure of the F14'A mutant of GLIC in complex with propofol · PFL B407 · binds TYR119, PRO120, PHE121, TYR197, ILE201, ILE202, MET205, TYR254 and 3 more
- 5MVM · X-ray structure of the F14'A -N15'A double mutant of GLIC in complex with propofol · PFL A510 · binds ILE236, ALA239, ILE240, GLU243, TYR263, ASN200, ILE201, PRO204 and 3 more
- 5MVN · X-ray structure of the M205W mutant of GLIC in complex with propofol · PFL B410 · binds TYR119, PRO120, PHE121, TYR197, ILE201, ILE202, TRP205, VAL242 and 3 more
- 5MZR · X-ray structure of the H235Q mutant of GLIC in complex with propofol · PFL A412 · binds TYR119, PRO120, PHE121, TYR197, ILE201, ILE202, MET205, VAL242 and 4 more
- 9BC6 · HCN1 M305L with propofol · PFL A703 · binds ILE380, ALA383, THR384, LEU305, CYS309, MET353, MET356, LEU357 and 3 more
- 5MUO · X-ray structure of the 2-22' locally-closed mutant of glic in complex with propofol · PFL D402 · binds SER230, THR226, SER230, THR226, SER230, ILE233, THR226, SER230 and 1 more
- 5MUR · X-ray structure of the F14'A mutant of glic in complex with propofol · PFL B407 · binds TYR119, PRO120, PHE121, TYR197, ILE201, ILE202, MET205, THR255 and 1 more
- 5MVM · X-ray structure of the F14'A -N15'A double mutant of glic in complex with propofol · PFL A510 · binds ILE236, ALA239, ILE240, GLU243, TYR263, ASN200, ILE201, PRO204 and 3 more
- 5MVN · X-ray structure of the M205W mutant of glic in complex with propofol · PFL B410 · binds TYR119, PRO120, TYR197, ILE201, ILE202, TRP205, VAL242, TYR254 and 2 more
- 5MZR · X-ray structure of the H235Q mutant of glic in complex with propofol · PFL A412 · binds TYR119, PRO120, TYR197, ILE201, ILE202, MET205, VAL242, TYR254 and 2 more
- 6X3T · Human gabaa receptor ALPHA1-BETA2-GAMMA2 subtype in complex with GABA plus propofol · PFL B601 · binds ASN265, ASP282, LEU285, MET286, PHE289, ILE228, GLN229, LEU232 and 2 more
Residues it binds most
ILE 38, TYR 34, PRO 30, MET 27, THR 26, ALA 14, LEU 14, PHE 17, VAL 17, ASN 12 (residue and the binding sites it lines).
Found with
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