MolNFT v1 · #126671 · protein

Human angiogenin PD/ALS variant R121C

5M9V: “Human angiogenin PD/ALS variant R121C”. X-ray diffraction, 1 ligand (GSH). MolNFT v1 #126671 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5M9V
Type: protein
Length: 121 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Angiogenin
EC: 3.1.27.-
UniProt: P03950
Ligands: GSH

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Angiogenin (EC 3.1.27.-)	protein	121	26% helix, 36% strand	P03950

Ligands and binding sites

GSH · Glutathione · ligand · chains A
TLA · L(+)-tartaric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 3 disulfide, 1 covalent (disulfide, covalent ligand).

Compared structures

5M9V · Human angiogenin PD/ALS variant R121C · the same entry in another collection · chain A against A, TM-score 1.00
P03950 · AlphaFold monomer V2.0 prediction for angiogenin (P03950) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03950
Elsewhere: RCSB PDB 5M9V · PDBe 5M9V · UniProt P03950

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