UniProt P03950
Angiogenin (P03950)
Angiogenin (UniProt P03950), EC 3.1.27.-: 101 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P03950
- Protein
- Angiogenin
- EC
- 3.1.27.-
- Experimental structures
- 101
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 3 · 2 records with a druggable one
Structures
102 records of P03950 in the MolNFT archive: 101 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1A4Y | Ribonuclease inhibitor-angiogenin complex | x-ray diffraction | B, E | — | — |
| 1A4Y | Ribonuclease inhibitor-angiogenin complex | x-ray diffraction | B, E | — | — |
| 1ANG | Crystal structure of human angiogenin reveals the structural basis for its functional divergence… | x-ray diffraction | A | — | — |
| 1ANG | Crystal structure of human angiogenin reveals the structural basis for its functional divergence… | x-ray diffraction | A | — | — |
| 1AWZ | 3D solution structure of human angiogenin determined by 1H, 15N NMR spectroscopy, 30 structures | solution nmr | A | — | — |
| 1AWZ | 3D solution structure of human angiogenin determined by 1H, 15N NMR spectroscopy, 30 structures | solution nmr | A | — | — |
| 1B1E | Crystal structure of human angiogenin variant K40Q | x-ray diffraction | A | — | — |
| 1B1E | Crystal structure of human angiogenin variant K40Q | x-ray diffraction | A | — | — |
| 1B1I | Crystal structure of human angiogenin | x-ray diffraction | A | — | — |
| 1B1I | Crystal structure of human angiogenin | x-ray diffraction | A | — | — |
| 1B1J | Crystal structure of human angiogenin variant H13A. | x-ray diffraction | A | — | — |
| 1B1J | Crystal structure of human angiogenin variant H13A. | x-ray diffraction | A | — | — |
| 1GV7 | ARH-I, an angiogenin/RNase A chimera | x-ray diffraction | A | — | — |
| 1GV7 | Arh-I, an ANGIOGENIN/RNASE a chimera | x-ray diffraction | A | — | — |
| 1H0D | Crystal structure of Human Angiogenin in complex with Fab fragment of its monoclonal antibody mAb… | x-ray diffraction | C | — | — |
| 1H0D | Crystal structure of human angiogenin in complex with Fab fragment of its monoclonal antibody mab… | x-ray diffraction | C | — | — |
| 1H52 | Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by… | x-ray diffraction | A | — | — |
| 1H52 | Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by… | x-ray diffraction | A | — | — |
| 1H53 | Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by… | x-ray diffraction | A | — | — |
| 1H53 | Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by… | x-ray diffraction | A | — | — |
| 1HBY | Binding of Phosphate and Pyrophosphate ions at the active site of human angiogenin as revealed by… | x-ray diffraction | A | — | — |
| 1HBY | Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by… | x-ray diffraction | A | — | — |
| 1K58 | Crystal Structure of Human Angiogenin Variant D116H | x-ray diffraction | A | — | — |
| 1K58 | Crystal structure of human angiogenin variant D116H | x-ray diffraction | A | — | — |
| 1K59 | Crystal Structure of Human Angiogenin Variant Q117G | x-ray diffraction | A | — | — |
| 1K59 | Crystal structure of human angiogenin variant Q117G | x-ray diffraction | A | — | — |
| 1K5A | Crystal structure of human angiogenin double variant I119A/F120A | x-ray diffraction | A | — | — |
| 1K5A | Crystal structure of human angiogenin double variant I119A/F120A | x-ray diffraction | A | — | — |
| 1K5B | Crystal Structure of Human Angiogenin Variant des(121-123) | x-ray diffraction | A | — | — |
| 1K5B | Crystal structure of human angiogenin variant DES(121-123) | x-ray diffraction | A | — | — |
| 1UN3 | Crystal structure of human angiogenin variant T44D | x-ray diffraction | A | — | — |
| 1UN3 | Crystal structure of human angiogenin variant T44D | x-ray diffraction | A | — | — |
| 1UN4 | Crystal structure of human angiogenin variant T80A | x-ray diffraction | A | — | — |
| 1UN4 | Crystal structure of human angiogenin variant T80A | x-ray diffraction | A | — | — |
| 1UN5 | Arh-II, an ANGIOGENIN/RNASE a chimera | x-ray diffraction | A | — | — |
| 1UN5 | Arh-II, an ANGIOGENIN/RNASE a chimera | x-ray diffraction | A | — | — |
| 2ANG | Crystal structure of human angiogenin of the met(-1) form | x-ray diffraction | A | — | — |
| 2ANG | Crystal structure of human angiogenin of the met(-1) form | x-ray diffraction | A | — | — |
| 4AHD | Q12L - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A, B | — | — |
| 4AHD | Q12L - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A, B | — | — |
| 4AHE | K17I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHE | K17I - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHF | K17E - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHF | K17E - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHG | S28N - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHG | S28N - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHH | R31K - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHH | R31K - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHI | K40I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHI | K40I - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHJ | I46V - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHJ | I46V - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHK | K54E - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A, B | — | — |
| 4AHK | K54E - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A, B | — | — |
| 4AHL | P112L - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHL | P112L - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHM | V113I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHM | V113I - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHN | R121H - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
| 4AHN | R121H - angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | x-ray diffraction | A | — | — |
42 records more on the page itself.
Ligands
Experiment against prediction
- 5M9S chain A against the predicted model P03950: TM-score 0.99, RMSD 0.30 Å
- 5M9S chain A against the predicted model P03950: TM-score 0.99, RMSD 0.30 Å
- 4AHM chain A against the predicted model P03950: TM-score 0.99, RMSD 0.32 Å
- 4AHM chain A against the predicted model P03950: TM-score 0.99, RMSD 0.32 Å
- 4AHJ chain A against the predicted model P03950: TM-score 0.99, RMSD 0.33 Å
- 4AHJ chain A against the predicted model P03950: TM-score 0.99, RMSD 0.33 Å
- 4AHK chain B against the predicted model P03950: TM-score 0.99, RMSD 0.33 Å
- 4AHK chain B against the predicted model P03950: TM-score 0.99, RMSD 0.33 Å
- 5M9C chain A against the predicted model P03950: TM-score 0.99, RMSD 0.34 Å
- 5M9C chain A against the predicted model P03950: TM-score 0.99, RMSD 0.34 Å
Elsewhere
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