MolNFT v1 · #126572 · protein
Crystal structure of human rhogap mutated in its arginine finger (R85A) in complex with RHOA.GDP.MGF3- human
5M6X: “Crystal structure of human rhogap mutated in its arginine finger (R85A) in complex with RHOA.GDP.MGF3- human”. X-ray diffraction, 3 ligands (GDP, MGF, MG). MolNFT v1 #126572 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5M6X
- Type
- protein
- Length
- 731 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q07960, P61586
- Ligands
- GDP, MGF, MG
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 188 | — | Q07960 |
| B | — | protein | 178 | — | P61586 |
| H | — | protein | 187 | — | Q07960 |
| I | — | protein | 178 | — | P61586 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B, H, I
- MGF · Trifluoromagnesate · ligand · 2 copies · chains B, I
- MG · Magnesium ion · metal · 2 copies · chains B, I
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5M6X · Crystal Structure of human RhoGAP mutated in its arginine finger (R85A) in complex with… · the same entry in another collection · chain I against I, TM-score 1.00
- Q07960 · AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 1 (Q07960) · a predicted model of the same protein · chain H against A, TM-score 0.99
- P61586 · AlphaFold monomer V2.0 prediction for transforming protein rhoa (P61586) · a predicted model of the same protein · chain I against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07960
- Every structure of UniProt P61586
- Elsewhere: RCSB PDB 5M6X · PDBe 5M6X · UniProt Q07960 · UniProt P61586
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