MolNFT v1 · #126532 · protein

COPS5(2-257) in complex with a azaindole (compound 4)

5M5Q: “COPS5(2-257) in complex with a azaindole (compound 4)”. X-ray diffraction, 2 ligands (7K1, ZN). MolNFT v1 #126532 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5M5Q
Type: protein
Length: 219 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q92905
Ligands: 7K1, ZN

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	219	—	Q92905

Ligands and binding sites

7K1 · 1-[(3~{R})-3-(1~{H}-benzimidazol-2-yl)morpholin-4-yl]-3-[2-(4-methyl-2-phenyl-phenyl)-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]propan-1-one · ligand · chains A
ZN · Zinc ion · metal · chains A
MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5M5Q · COPS5(2-257) in complex with a azaindole (compound 4) · the same entry in another collection · chain A against A, TM-score 1.00
Q92905 · AlphaFold monomer V2.0 prediction for COP9 signalosome complex subunit 5 (Q92905) · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92905
Elsewhere: RCSB PDB 5M5Q · PDBe 5M5Q · UniProt Q92905

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