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MolNFT v1 · #125626 · protein

RAB6A:KIF20A complex

5LEF: “RAB6A:KIF20A complex”. X-ray diffraction, 3 ligands (GTP, MG, SO4). MolNFT v1 #125626 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5LEF
Type
protein
Length
421 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P20340, P97329
Ligands
GTP, MG, SO4

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein166—P20340
B—protein159—P20340
C—protein49—P97329
D—protein47—P97329

Ligands and binding sites

  • GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, B
  • MG · Magnesium ion · metal · 2 copies · chains A, B
  • SO4 · Sulfate ion · ion · 3 copies · chains A, B
  • GOL · Glycerol · additive · chains A
  • IPA · Isopropyl alcohol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5LEF · Rab6A:Kif20A complex · the same entry in another collection · chain D against D, TM-score 1.00
  • P20340 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-6A (P20340) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • P97329 · AlphaFold monomer V2.0 prediction for kinesin-like protein KIF20A (P97329) · a predicted model of the same protein · chain D against A, TM-score 0.86

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