UniProt P97329
Kinesin-like protein KIF20A (P97329)
Kinesin-like protein KIF20A (UniProt P97329): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P97329
- Protein
- Kinesin-like protein KIF20A
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 28 · 5 records with a druggable one
Structures
13 records of P97329 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LEF | Rab6A:Kif20A complex | x-ray diffraction | C, D | — | — |
| 5LEF | RAB6A:KIF20A complex | x-ray diffraction | C, D | — | — |
| 5ND2 | Microtubule-bound MKLP2 motor domain in the presence of ADP | electron microscopy | C | ADP, MG | 4 (best 0.81) |
| 5ND2 | Microtubule-bound MKLP2 motor domain in the presence of ADP | electron microscopy | C | ADP, MG | — |
| 5ND3 | Microtubule-bound MKLP2 motor domain in the with no nucleotide | electron microscopy | C | — | — |
| 5ND3 | Microtubule-bound MKLP2 motor domain in the with no nucleotide | electron microscopy | C | — | — |
| 5ND4 | Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx | electron microscopy | C | ADP, MG, ALF | 7 (best 0.89) |
| 5ND4 | Microtubule-bound MKLP2 motor domain in the presence of ADP.ALFX | electron microscopy | C | ADP, MG, ALF | — |
| 5ND7 | Microtubule-bound MKLP2 motor domain in the presence of AMPPNP | electron microscopy | C | MG, ANP | 4 (best 0.88) |
| 5ND7 | Microtubule-bound MKLP2 motor domain in the presence of amppnp | electron microscopy | C | MG, ANP | — |
| 8F18 | Apo KIF20A[1-565] class-2 in complex with a microtubule | electron microscopy | K | — | 5 (best 0.80) |
| 8F1A | Apo KIF20A[1-565] class-1 in complex with a microtubule | electron microscopy | K | — | 8 (best 0.79) |
| P97329 | AlphaFold monomer V2.0 prediction for kinesin-like protein KIF20A (P97329) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5ND4 chain C against the predicted model P97329: TM-score 0.94, RMSD 1.63 Å
- 5ND4 chain C against the predicted model P97329: TM-score 0.94, RMSD 1.63 Å
- 5ND2 chain C against the predicted model P97329: TM-score 0.92, RMSD 1.94 Å
- 5ND2 chain C against the predicted model P97329: TM-score 0.92, RMSD 1.94 Å
- 5ND3 chain C against the predicted model P97329: TM-score 0.92, RMSD 2.08 Å
- 5ND3 chain C against the predicted model P97329: TM-score 0.92, RMSD 2.08 Å
- 5ND7 chain C against the predicted model P97329: TM-score 0.91, RMSD 2.13 Å
- 5ND7 chain C against the predicted model P97329: TM-score 0.91, RMSD 2.13 Å
- 8F18 chain K against the predicted model P97329: TM-score 0.88, RMSD 2.39 Å
- 8F1A chain K against the predicted model P97329: TM-score 0.87, RMSD 2.90 Å
Elsewhere
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