MolNFT v1 · #124879 · protein + DNA

Flap endonuclease 1 (FEN1) R100A with 5'-flap substrate DNA and SM3+

5KSE: “Flap endonuclease 1 (FEN1) R100A with 5'-flap substrate DNA and SM3+”. X-ray diffraction, 2 ligands (SM, K). MolNFT v1 #124879 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5KSE
Type: protein + DNA
Length: 381 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P39748
Ligands: SM, K

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	341	—	P39748
D	—	dna	18	—	—
E	—	dna	15	—	—
F	—	dna	7	—	—

Ligands and binding sites

SM · Samarium (III) ion · metal · 5 copies · chains A, E
K · Potassium ion · metal · chains A, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5KSE · Flap endonuclease 1 (FEN1) R100A with 5'-flap substrate DNA and Sm3+ · the same entry in another collection · chain A against A, TM-score 1.00
P39748 · AlphaFold monomer V2.0 prediction for flap endonuclease 1 (P39748) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P39748
Elsewhere: RCSB PDB 5KSE · PDBe 5KSE · UniProt P39748

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