MolNFT v1 · #124641 · protein + DNA

Wilms tumor protein (WT1) ZNF2-4 in complex with DNA

5KL2: “Wilms tumor protein (WT1) ZNF2-4 in complex with DNA”. X-ray diffraction, 2 ligands (ZN, NA). MolNFT v1 #124641 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5KL2
Type: protein + DNA
Length: 110 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P19544
Ligands: ZN, NA

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	88	—	P19544
B	—	dna	11	—	—
C	—	dna	11	—	—

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains A
NA · Sodium ion · metal · chains A, C
EDO · 1,2-ethanediol · additive · 5 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5KL2 · Wilms Tumor Protein (WT1) ZnF2-4 in complex with DNA · the same entry in another collection · chain A against A, TM-score 1.00
P19544 · AlphaFold monomer V2.0 prediction for wilms tumor protein (P19544) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19544
Elsewhere: RCSB PDB 5KL2 · PDBe 5KL2 · UniProt P19544

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