UniProt P19544
Wilms tumor protein (P19544)
Wilms tumor protein (UniProt P19544): 38 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P19544
- Protein
- Wilms tumor protein
- Experimental structures
- 38
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 27 · 4 records with a druggable one
Structures
39 records of P19544 in the MolNFT archive: 38 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1XF7 | High Resolution NMR Structure of the Wilms' Tumor Suppressor Protein (WT1) Finger 3 | solution nmr | A | — | — |
| 1XF7 | High resolution NMR structure of the wilms' tumor suppressor protein (WT1) finger 3 | solution nmr | A | — | — |
| 3HPJ | Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide | x-ray diffraction | C, F | — | — |
| 3HPJ | Human class I MHC HLA-A2 in complex with the wt-1 (126-134) peptide | x-ray diffraction | C, F | — | — |
| 3MYJ | Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) (R1Y) peptide variant. | x-ray diffraction | C, F | — | — |
| 3MYJ | Human class I MHC HLA-A2 in complex with the wt-1 (126-134) (R1Y) peptide variant. | x-ray diffraction | C, F | — | — |
| 4R2E | Wilms Tumor Protein (WT1) zinc fingers in complex with methylated DNA | x-ray diffraction | A | — | — |
| 4R2E | Wilms tumor protein (WT1) zinc fingers in complex with methylated DNA | x-ray diffraction | A | — | — |
| 4R2P | Wilms Tumor Protein (WT1) zinc fingers in complex with hydroxymethylated DNA | x-ray diffraction | A | — | — |
| 4R2P | Wilms tumor protein (WT1) zinc fingers in complex with hydroxymethylated DNA | x-ray diffraction | A | — | — |
| 4R2Q | Wilms Tumor Protein (WT1) zinc fingers in complex with formylated DNA | x-ray diffraction | A | — | — |
| 4R2Q | Wilms tumor protein (WT1) zinc fingers in complex with formylated DNA | x-ray diffraction | A | — | — |
| 4R2R | Wilms Tumor Protein (WT1) zinc fingers in complex with carboxylated DNA | x-ray diffraction | A | — | — |
| 4R2R | Wilms tumor protein (WT1) zinc fingers in complex with carboxylated DNA | x-ray diffraction | A | — | — |
| 4R2S | Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA | x-ray diffraction | A | — | — |
| 4R2S | Wilms tumor protein (WT1) Q369P zinc fingers in complex with methylated DNA | x-ray diffraction | A | — | — |
| 5KL2 | Wilms Tumor Protein (WT1) ZnF2-4 in complex with DNA | x-ray diffraction | A | ZN, NA | — |
| 5KL2 | Wilms tumor protein (WT1) ZNF2-4 in complex with DNA | x-ray diffraction | A | ZN, NA | — |
| 5KL3 | Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with DNA | x-ray diffraction | A | ZN | — |
| 5KL3 | Wilms tumor protein (WT1) ZNF2-4 Q369H in complex with DNA | x-ray diffraction | A | ZN | — |
| 5KL4 | Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with formylated DNA | x-ray diffraction | A, D | ZN, CA, NA | 6 (best 0.64) |
| 5KL4 | Wilms tumor protein (WT1) ZNF2-4 Q369H in complex with formylated DNA | x-ray diffraction | A, D | ZN, CA | — |
| 5KL5 | Wilms Tumor Protein (WT1) ZnF2-4 Q369H in complex with carboxylated DNA | x-ray diffraction | A | ZN | — |
| 5KL5 | Wilms tumor protein (WT1) ZNF2-4 Q369H in complex with carboxylated DNA | x-ray diffraction | A | ZN | — |
| 5KL6 | Wilms Tumor Protein (WT1) Q369R ZnF2-4 in complex with DNA | x-ray diffraction | A | ZN | — |
| 5KL6 | Wilms tumor protein (WT1) Q369R ZNF2-4 in complex with DNA | x-ray diffraction | A | ZN | — |
| 5KL7 | Wilms Tumor Protein (WT1) ZnF2-4Q369R in complex with carboxylated DNA | x-ray diffraction | A | ZN | — |
| 5KL7 | Wilms tumor protein (WT1) ZNF2-4Q369R in complex with carboxylated DNA | x-ray diffraction | A | ZN | — |
| 6B0O | Zinc finger Domain of WT1(-KTS form) with 12+1mer Oligonucleotide with 3' Triplet TGT | x-ray diffraction | A, D | ZN | 4 (best 0.75) |
| 6B0O | Zinc finger domain of WT1(-kts form) with 12+1MER oligonucleotide with 3' triplet tgt | x-ray diffraction | A, D | ZN | — |
| 6B0P | Zinc finger Domain of WT1(-KTS form) with 12+1mer Oligonucleotide with 3' Triplet GGT | x-ray diffraction | D, A | ZN | 6 (best 0.70) |
| 6B0P | Zinc finger domain of WT1(-kts form) with 12+1MER oligonucleotide with 3' triplet ggt | x-ray diffraction | D, A | ZN | — |
| 6B0Q | Zinc finger domain of WT1(-kts form) with 13+1MER oligonucleotide with 3' triplet tgt | x-ray diffraction | D, A | ZN, SO4 | — |
| 6B0R | Zinc finger Domain of WT1(-KTS form) with M342R Mutation and 14+1mer Oligonucleotide with 3'… | x-ray diffraction | D, A | ZN | — |
| 6B0R | Zinc finger domain of WT1(-kts form) with M342R mutation and 14+1MER oligonucleotide with 3'… | x-ray diffraction | D, A | ZN | — |
| 6BLW | Zinc finger domain of WT1(+KTS form) with M342R mutation and 17+1MER oligonucleotide with triplet… | x-ray diffraction | A | ZN | — |
| 6WLH | RNA complex of WT1 zinc finger transcription factor | solution nmr | A | ZN | — |
| 7SR5 | Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL | x-ray diffraction | A, C | — | 9 (best 0.68) |
| P19544 | AlphaFold monomer V2.0 prediction for wilms tumor protein (P19544) | predicted | A | — | 2 (best 0.45) |
Ligands
Experiment against prediction
- 5KL2 chain A against the predicted model P19544: TM-score 0.95, RMSD 0.89 Å
- 5KL2 chain A against the predicted model P19544: TM-score 0.95, RMSD 0.89 Å
- 4R2S chain A against the predicted model P19544: TM-score 0.93, RMSD 1.30 Å
- 4R2S chain A against the predicted model P19544: TM-score 0.93, RMSD 1.30 Å
- 4R2E chain A against the predicted model P19544: TM-score 0.92, RMSD 1.07 Å
- 4R2E chain A against the predicted model P19544: TM-score 0.92, RMSD 1.07 Å
- 5KL3 chain A against the predicted model P19544: TM-score 0.92, RMSD 0.90 Å
- 5KL3 chain A against the predicted model P19544: TM-score 0.92, RMSD 0.90 Å
- 5KL6 chain A against the predicted model P19544: TM-score 0.92, RMSD 1.09 Å
- 5KL6 chain A against the predicted model P19544: TM-score 0.92, RMSD 1.09 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.