MolNFT v1 · #500382 · protein
AlphaFold monomer V2.0 prediction for wilms tumor protein (P19544)
P19544: “AlphaFold monomer V2.0 prediction for wilms tumor protein (P19544)”. 2 pockets (best druggability 0.45). MolNFT v1 #500382 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P19544
- Type
- protein
- Length
- 449 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1f0b1aeA56C13da54F3c6EE6CE41C19fcF2DD979
- Molecule
- Wilms tumor protein
- UniProt
- P19544
- Pockets
- 2 · best druggability 0.45
Structure
1 distinct chain · 13% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Wilms tumor protein | protein | 449 | 13% helix, 3% strand | P19544 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.45 | 0.75 | 28 | empty |
| 2 | 162 | 0.42 | 0.74 | 22 | empty |
Compared structures
- 6B0O · Zinc finger domain of WT1(-kts form) with 12+1MER oligonucleotide with 3' triplet tgt · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 6B0R · Zinc finger Domain of WT1(-KTS form) with M342R Mutation and 14+1mer Oligonucleotide with… · an experimental structure of the same protein · chain A against D, TM-score 0.25
- 6B0R · Zinc finger domain of WT1(-kts form) with M342R mutation and 14+1MER oligonucleotide with… · an experimental structure of the same protein · chain A against D, TM-score 0.25
- 6B0Q · Zinc finger domain of WT1(-kts form) with 13+1MER oligonucleotide with 3' triplet tgt · an experimental structure of the same protein · chain A against A, TM-score 0.23
- 6B0P · Zinc finger domain of WT1(-kts form) with 12+1MER oligonucleotide with 3' triplet ggt · an experimental structure of the same protein · chain A against D, TM-score 0.21
- 6WLH · RNA complex of WT1 zinc finger transcription factor · an experimental structure of the same protein · chain A against A, TM-score 0.21
- 4R2S · Wilms tumor protein (WT1) Q369P zinc fingers in complex with methylated DNA · an experimental structure of the same protein · chain A against A, TM-score 0.19
- 4R2S · Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA · an experimental structure of the same protein · chain A against A, TM-score 0.19
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19544
- Elsewhere: UniProt P19544 · AlphaFold DB P19544
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