MolNFT v1 · #124560 · protein
The structure of vioxx bound to human COX-2
5KIR: “The structure of vioxx bound to human COX-2”. X-ray diffraction, 6 ligands (RCX, COH, NAG). MolNFT v1 #124560 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5KIR
- Type
- protein
- Length
- 1,102 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P35354
- Ligands
- RCX, COH, NAG, MAN, PO4, NH4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 551 | — | P35354 |
Ligands and binding sites
- RCX · Rofecoxib · ligand · 2 copies · chains A, B
- COH · Protoporphyrin IX containing co · ligand · 2 copies · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A, B
- MAN · alpha-D-mannopyranose · sugar · 2 copies
- PO4 · Phosphate ion · ion · 6 copies · chains A, B
- NH4 · Ammonium ion · ion · 2 copies · chains A, B
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35354
- Elsewhere: RCSB PDB 5KIR · PDBe 5KIR · UniProt P35354
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