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MolNFT v1 · #123696 · protein

Structural model of a protein alpha subunit in complex with GDP obtained with saxs and NMR residual couplings

5JS8 · Guanine nucleotide-binding protein G(I) subunit alpha-1: “Structural model of a protein alpha subunit in complex with GDP obtained with saxs and NMR residual couplings”. Solution nmr, 2 pockets (best druggability 0.61). MolNFT v1…

PDB
5JS8
Type
protein
Length
323 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Guanine nucleotide-binding protein G(I) subunit alpha-1
UniProt
P63096
Pockets
2 · best druggability 0.61

Structure

solution nmr · 1 distinct chain · 52% helix, 11% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGuanine nucleotide-binding protein G(I) subunit alpha-1protein32352% helix, 11% strandP63096

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14820.610.7549empty
2650.340.7715empty

Compared structures

  • 5JS8 · Structural Model of a Protein alpha subunit in complex with GDP obtained with SAXS and… · the same entry in another collection · chain A against A, TM-score 1.00
  • P63096 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.64

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