MolNFT v1 · #1231 · protein
Bovine annexin VI (calcium-bound)
1AVC: “Bovine annexin VI (calcium-bound)”. X-ray diffraction, 1 ligand (CA), 8 pockets (best druggability 0.83). MolNFT v1 #1231 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1AVC
- Type
- protein
- Length
- 642 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Annexin VI
- UniProt
- P79134
- Ligands
- CA
- Pockets
- 8 · best druggability 0.83
Structure
x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Annexin VI | protein | 642 | 71% helix, 0% strand | P79134 |
Ligands and binding sites
- CA · Calcium ion · metal · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 961 | 0.83 | 0.84 | 81 | empty |
| 2 | 150 | 0.62 | 0.85 | 28 | empty |
| 3 | 79 | 0.52 | 0.85 | 20 | empty |
| 4 | 176 | 0.49 | 0.77 | 22 | empty |
| 5 | 59 | 0.47 | 0.85 | 21 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P79134
- Elsewhere: RCSB PDB 1AVC · PDBe 1AVC · UniProt P79134
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