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Bovine annexin VI (calcium-bound)

Analyse Bovine annexin VI (calcium-bound) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1AVC
Type: protein
Length: 642 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Annexin VI
UniProt: P79134
Ligands: CA
Pockets: 8 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Annexin VI	protein	642	71% helix, 0% strand	P79134

Ligands and binding sites

CA · Calcium ion · metal · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	961	0.83	0.84	81	empty
2	150	0.62	0.85	28	empty
3	79	0.52	0.85	20	empty
4	176	0.49	0.77	22	empty
5	59	0.47	0.85	21	empty

Compared structures

1AVC · Bovine annexin VI (calcium-bound) · the same entry in another collection · chain A against A, TM-score 1.00
P79134 · AlphaFold monomer V2.0 prediction for annexin A6 (P79134) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P79134
Elsewhere: RCSB PDB 1AVC · PDBe 1AVC · UniProt P79134

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