MolNFT v1 · #121980 · protein
1.95A resolution structure of nanoluc luciferase
5IBO · Oplophorus-luciferin 2-monooxygenase catalytic subunit: “1.95A resolution structure of nanoluc luciferase”. X-ray diffraction, 1 ligand (DKA), 3 pockets (best druggability 0.77). MolNFT v1 #121980 on GenesisL1: 3D structure, binding…
- PDB
- 5IBO
- Type
- protein
- Length
- 335 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Oplophorus-luciferin 2-monooxygenase catalytic subunit
- EC
- 1.13.12.13
- UniProt
- Q9GV45
- Ligands
- DKA
- Pockets
- 3 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 17% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Oplophorus-luciferin 2-monooxygenase catalytic subunit (EC 1.13.12.13) | protein | 171 | 18% helix, 52% strand | Q9GV45 |
| B | Oplophorus-luciferin 2-monooxygenase catalytic subunit (EC 1.13.12.13) | protein | 164 | 16% helix, 51% strand | Q9GV45 |
Ligands and binding sites
- DKA · Decanoic acid · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 494 | 0.77 | 0.85 | 57 | empty |
| 2 | 78 | 0.65 | 0.91 | 21 | empty |
| 3 | 351 | 0.63 | 0.79 | 34 | empty |
Interfaces
1 interface between chains.
- A–B · 986 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GV45
- Elsewhere: RCSB PDB 5IBO · PDBe 5IBO · UniProt Q9GV45
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.