UniProt Q9GV45
Oplophorus-luciferin 2-monooxygenase catalytic subunit (Q9GV45)
Oplophorus-luciferin 2-monooxygenase catalytic subunit (UniProt Q9GV45), EC 1.13.12.13: 6 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 11 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9GV45
- Protein
- Oplophorus-luciferin 2-monooxygenase catalytic subunit
- EC
- 1.13.12.13
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 11 · 2 records with a druggable one
Structures
7 records of Q9GV45 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5B0U | Crystal structure of the mutated 19 kDa protein of Oplophorus luciferase (nanoKAZ) | x-ray diffraction | A, B | — | — |
| 5B0U | Crystal structure of the mutated 19 kda protein of oplophorus luciferase (nanokaz) | x-ray diffraction | A, B | — | — |
| 5IBO | 1.95A resolution structure of nanoluc luciferase | x-ray diffraction | A, B | — | — |
| 7SNS | 1.55A Resolution Structure of NanoLuc Luciferase | x-ray diffraction | A, B, C, D | — | — |
| 7SNW | 1.80A Resolution Structure of NanoLuc Luciferase with Bound Inhibitor PC 16026576 | x-ray diffraction | A, B, C | MG, SO4, 9YR, 9Y4, CL | 6 (best 0.86) |
| 8JPN | Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi | electron microscopy | R | U9S | 5 (best 0.70) |
| Q9GV45 | AlphaFold monomer V2.0 prediction for oplophorus-luciferin 2-monooxygenase catalytic subunit… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5IBO chain A against the predicted model Q9GV45: TM-score 0.97, RMSD 0.73 Å
- 5IBO chain B against the predicted model Q9GV45: TM-score 0.97, RMSD 0.92 Å
- 7SNS chain B against the predicted model Q9GV45: TM-score 0.97, RMSD 0.98 Å
- 7SNS chain C against the predicted model Q9GV45: TM-score 0.96, RMSD 1.11 Å
- 7SNS chain A against the predicted model Q9GV45: TM-score 0.96, RMSD 1.11 Å
- 5B0U chain B against the predicted model Q9GV45: TM-score 0.90, RMSD 1.82 Å
- 5B0U chain B against the predicted model Q9GV45: TM-score 0.90, RMSD 1.82 Å
- 5B0U chain A against the predicted model Q9GV45: TM-score 0.89, RMSD 1.91 Å
- 5B0U chain A against the predicted model Q9GV45: TM-score 0.89, RMSD 1.91 Å
- 7SNW chain A against the predicted model Q9GV45: TM-score 0.89, RMSD 2.08 Å
Elsewhere
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