MolNFT v1 · #121918 · protein
Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A
5I9J · Star-related lipid transfer protein 3: “Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.82). MolNFT v1 #121918 on GenesisL1: 3D…
- PDB
- 5I9J
- Type
- protein
- Length
- 214 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Star-related lipid transfer protein 3
- UniProt
- Q14849
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Star-related lipid transfer protein 3 | protein | 214 | 32% helix, 37% strand | Q14849 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
- TLA · L(+)-tartaric acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 277 | 0.82 | 0.94 | 55 | EDO |
| 2 | 58 | 0.31 | 0.76 | 18 | EDO |
Compared structures
- 5I9J · Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A · the same entry in another collection · chain A against A, TM-score 1.00
- Q14849 · AlphaFold monomer V2.0 prediction for star-related lipid transfer protein 3 (Q14849) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14849
- Elsewhere: RCSB PDB 5I9J · PDBe 5I9J · UniProt Q14849
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