MolNFT v1 · #120915 · protein

The third PDZ domain from the synaptic protein psd-95 (H372A mutant) in complex with a C-terminal peptide derived from cript

5HFB · Disks large homolog 4: “The third PDZ domain from the synaptic protein psd-95 (H372A mutant) in complex with a C-terminal peptide…”. X-ray diffraction. MolNFT v1 #120915 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5HFB
Type: protein
Length: 123 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Disks large homolog 4; Cysteine-rich PDZ-binding protein
UniProt: P31016, Q792Q4

Structure

x-ray diffraction · 2 distinct chains · 20% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Disks large homolog 4	protein	117	21% helix, 33% strand	P31016
B	Cysteine-rich PDZ-binding protein	protein	6	0% helix, 50% strand	Q792Q4

Interfaces

1 interface between chains.

A–B · 452 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

5HFB · The third PDZ domain from the synaptic protein PSD-95 (H372A mutant) in complex with a… · the same entry in another collection · chain A against A, TM-score 1.00
P31016 · AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016) · a predicted model of the same protein · chain A against A, TM-score 0.82
Q792Q4 · AlphaFold monomer V2.0 prediction for cysteine-rich PDZ-binding protein (Q792Q4) · a predicted model of the same protein · chain B against A, TM-score 0.55

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P31016
Every structure of UniProt Q792Q4
Elsewhere: RCSB PDB 5HFB · PDBe 5HFB · UniProt P31016 · UniProt Q792Q4

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