The third PDZ domain from the synaptic protein psd-95 in complex with a C-terminal peptide derived from cript

Structure

x-ray diffraction · 2 distinct chains · 17% helix, 33% strand (DSSP).

Ligands and binding sites

• GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 527 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

• 5HEB · The third PDZ domain from the synaptic protein PSD-95 in complex with a C-terminal… · the same entry in another collection · chain A against A, TM-score 1.00
• P31016 · AlphaFold monomer V2.0 prediction for disks large homolog 4 (P31016) · a predicted model of the same protein · chain A against A, TM-score 0.81
• Q792Q4 · AlphaFold monomer V2.0 prediction for cysteine-rich PDZ-binding protein (Q792Q4) · a predicted model of the same protein · chain B against A, TM-score 0.47

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P31016
• Every structure of UniProt Q792Q4
• Elsewhere: RCSB PDB 5HEB · PDBe 5HEB · UniProt P31016 · UniProt Q792Q4