MolNFT v1 · #117816 · protein

Crystal structure of NAD kinase W78F mutant from listeria monocytogenes in complex with NADP/MN++/PPI

5EJI · NAD kinase 1: “Crystal structure of NAD kinase W78F mutant from listeria monocytogenes in complex with NADP/MN++/PPI”. X-ray diffraction, 3 ligands (NAP, POP, MN), 1 pocket (best druggability 0.32). MolNFT v1 #117816 on GenesisL1…

PDB: 5EJI
Type: protein
Length: 260 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NAD kinase 1
EC: 2.7.1.23
UniProt: Q8Y8D7
Ligands: NAP, POP, MN
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 22% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NAD kinase 1 (EC 2.7.1.23)	protein	260	22% helix, 40% strand	Q8Y8D7

Ligands and binding sites

NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · chains A
POP · Pyrophosphate 2- · ligand · chains A
MN · Manganese (II) ion · metal · chains A
CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.32	0.75	14	empty

Compared structures

5EJI · Crystal structure of NAD kinase W78F mutant from Listeria monocytogenes in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8Y8D7
Elsewhere: RCSB PDB 5EJI · PDBe 5EJI · UniProt Q8Y8D7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.