MolNFT v1 · #115444 · protein

BT4246 with galactose

5CJZ · Susd homolog: “BT4246 with galactose”. X-ray diffraction, 4 ligands (GAL, CS, K), 7 pockets (best druggability 0.68). MolNFT v1 #115444 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5CJZ
Type: protein
Length: 603 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Susd homolog
UniProt: Q89ZX5
Ligands: GAL, CS, K, CA
Pockets: 7 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Susd homolog	protein	603	40% helix, 10% strand	Q89ZX5

Ligands and binding sites

GAL · beta-D-galactopyranose · sugar · chains A
CS · Cesium ion · metal · 3 copies · chains A
K · Potassium ion · metal · 2 copies · chains A
CA · Calcium ion · metal · chains A
EDO · 1,2-ethanediol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	267	0.68	0.84	30	K
2	282	0.60	0.79	28	empty
3	56	0.60	0.91	20	empty
4	80	0.39	0.78	15	empty
5	62	0.37	0.79	14	empty

Compared structures

5CJZ · BT4246 with galactose · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q89ZX5
Elsewhere: RCSB PDB 5CJZ · PDBe 5CJZ · UniProt Q89ZX5

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