MolNFT v1 · #11441 · protein
X-ray structure of a core U2AF65/U2AF35 heterodimer
1JMT · Splicing factor U2AF 35 kda subunit: “X-ray structure of a core U2AF65/U2AF35 heterodimer”. X-ray diffraction. MolNFT v1 #11441 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1JMT
- Type
- protein
- Length
- 121 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Splicing factor U2AF 35 kda subunit; Splicing factor U2AF 65 kda subunit
- UniProt
- Q01081, P26368
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Splicing factor U2AF 35 kda subunit | protein | 98 | 42% helix, 31% strand | Q01081 |
| B | Splicing factor U2AF 65 kda subunit | protein | 23 | 26% helix, 4% strand | P26368 |
Ligands and binding sites
- HEZ · Hexane-1,6-diol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 864 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 1JMT · X-ray Structure of a Core U2AF65/U2AF35 Heterodimer · the same entry in another collection · chain A against A, TM-score 1.00
- Q01081 · AlphaFold monomer V2.0 prediction for splicing factor U2AF 35 kda subunit (Q01081) · a predicted model of the same protein · chain A against A, TM-score 0.86
- P26368 · AlphaFold monomer V2.0 prediction for splicing factor U2AF 65 kda subunit (P26368) · a predicted model of the same protein · chain B against A, TM-score 0.46
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q01081
- Every structure of UniProt P26368
- Elsewhere: RCSB PDB 1JMT · PDBe 1JMT · UniProt Q01081 · UniProt P26368
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