X-ray structure of a core U2AF65/U2AF35 heterodimer

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 26% strand (DSSP).

Ligands and binding sites

• HEZ · Hexane-1,6-diol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 864 Ų buried · 14 hydrogen bonds · protein-protein

Compared structures

• 1JMT · X-ray Structure of a Core U2AF65/U2AF35 Heterodimer · the same entry in another collection · chain A against A, TM-score 1.00
• Q01081 · AlphaFold monomer V2.0 prediction for splicing factor U2AF 35 kda subunit (Q01081) · a predicted model of the same protein · chain A against A, TM-score 0.86
• P26368 · AlphaFold monomer V2.0 prediction for splicing factor U2AF 65 kda subunit (P26368) · a predicted model of the same protein · chain B against A, TM-score 0.46

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q01081
• Every structure of UniProt P26368
• Elsewhere: RCSB PDB 1JMT · PDBe 1JMT · UniProt Q01081 · UniProt P26368