UniProt P26368
Splicing factor U2AF 65 kDa subunit (P26368)
Splicing factor U2AF 65 kDa subunit (UniProt P26368): 63 experimental structures on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P26368
- Protein
- Splicing factor U2AF 65 kDa subunit
- Experimental structures
- 63
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 1 · 1 record with a druggable one
Structures
63 records of P26368 in the MolNFT archive: 63 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JMT | X-ray Structure of a Core U2AF65/U2AF35 Heterodimer | x-ray diffraction | B | — | — |
| 1JMT | X-ray structure of a core U2AF65/U2AF35 heterodimer | x-ray diffraction | B | — | — |
| 1O0P | Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal… | solution nmr | A | — | — |
| 1O0P | Solution structure of the third RNA recognition motif (rrm) of U2AF65 in complex with an N-terminal… | solution nmr | A | — | — |
| 1OPI | Solution structure of the third RNA recognition motif (rrm) of U2AF65 in complex with an N-terminal… | solution nmr | A | — | — |
| 1OPI | Solution structure of the third RNA recognition motif (rrm) of U2AF65 in complex with an N-terminal… | solution nmr | A | — | — |
| 1U2F | Solution structure of the first RNA-binding domain of HU2AF65 | solution nmr | A | — | — |
| 1U2F | Solution structure of the first RNA-binding domain of HU2AF65 | solution nmr | A | — | — |
| 2G4B | Structure of U2AF65 variant with polyuridine tract | x-ray diffraction | A | — | — |
| 2G4B | Structure of U2AF65 variant with polyuridine tract | x-ray diffraction | A | — | — |
| 2HZC | Crystal structure of the N-terminal RRM of the U2AF large subunit | x-ray diffraction | A | — | — |
| 2HZC | Crystal structure of the N-terminal rrm of the U2AF large subunit | x-ray diffraction | A | — | — |
| 2M0G | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3… | solution nmr | B | — | — |
| 2M0G | Structure, phosphorylation and U2AF65 binding of the nterminal domain of splicing factor 1 during 3… | solution nmr | B | — | — |
| 2U2F | Solution structure of the second RNA-binding domain of HU2AF65 | solution nmr | A | — | — |
| 2U2F | Solution structure of the second RNA-binding domain of HU2AF65 | solution nmr | A | — | — |
| 2YH0 | Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains | solution nmr | A | — | — |
| 2YH0 | Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains | solution nmr | A | — | — |
| 2YH1 | Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding | solution nmr | A | — | — |
| 2YH1 | Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding | solution nmr | A | — | — |
| 3VAF | Structure of U2AF65 variant with BrU3 DNA | x-ray diffraction | A, B | — | — |
| 3VAF | Structure of U2AF65 variant with BRU3 DNA | x-ray diffraction | A, B | — | — |
| 3VAG | Structure of U2AF65 variant with BrU3C2 DNA | x-ray diffraction | A, B | — | — |
| 3VAG | Structure of U2AF65 variant with BRU3C2 DNA | x-ray diffraction | A, B | — | — |
| 3VAH | Structure of U2AF65 variant with BrU3C4 DNA | x-ray diffraction | A, B | — | — |
| 3VAH | Structure of U2AF65 variant with BRU3C4 DNA | x-ray diffraction | A, B | — | — |
| 3VAI | Structure of U2AF65 variant with BrU3C5 DNA | x-ray diffraction | A, B | — | — |
| 3VAI | Structure of U2AF65 variant with BRU3C5 DNA | x-ray diffraction | A, B | — | — |
| 3VAJ | Structure of U2AF65 variant with BrU5C6 DNA | x-ray diffraction | A, B | — | — |
| 3VAJ | Structure of U2AF65 variant with BRU5C6 DNA | x-ray diffraction | A, B | — | — |
| 3VAK | Structure of U2AF65 variant with BrU5 DNA | x-ray diffraction | A, B | — | — |
| 3VAK | Structure of U2AF65 variant with BRU5 DNA | x-ray diffraction | A, B | — | — |
| 3VAL | Structure of U2AF65 variant with BrU5C1 DNA | x-ray diffraction | A, B, D, I | — | — |
| 3VAL | Structure of U2AF65 variant with BRU5C1 DNA | x-ray diffraction | A, B, D, I | — | — |
| 3VAM | Structure of U2AF65 variant with BrU5C2 DNA | x-ray diffraction | A, B | — | — |
| 3VAM | Structure of U2AF65 variant with BRU5C2 DNA | x-ray diffraction | A, B | — | — |
| 4FXW | Structure of phosphorylated SF1 complex with U2AF65-UHM domain | x-ray diffraction | A, C | — | — |
| 4FXW | Structure of phosphorylated SF1 complex with U2AF65-uhm domain | x-ray diffraction | A, C | — | — |
| 4TU7 | Structure of U2AF65 D231V variant with BrU5 DNA | x-ray diffraction | A, B | — | — |
| 4TU7 | Structure of U2AF65 D231V variant with BRU5 DNA | x-ray diffraction | A, B | — | — |
| 4TU8 | Structure of U2AF65 variant with BRU5A6 DNA | x-ray diffraction | A, B | — | — |
| 4TU8 | Structure of U2AF65 variant with BRU5A6 DNA | x-ray diffraction | A, B | — | — |
| 4TU9 | Structure of U2AF65 variant with BRU5G6 DNA | x-ray diffraction | A, B | — | — |
| 4TU9 | Structure of U2AF65 variant with BRU5G6 DNA | x-ray diffraction | A, B | — | — |
| 5EV1 | Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal | x-ray diffraction | A | NA | — |
| 5EV1 | Structure I of intact U2AF65 recognizing a 3' splice site signal | x-ray diffraction | A | — | — |
| 5EV2 | Structure II of intact U2AF65 recognizing the 3' splice site signal | x-ray diffraction | A | — | — |
| 5EV3 | Structure III of intact U2AF65 recognizing the 3' splice site signal | x-ray diffraction | A | — | — |
| 5EV4 | Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal | x-ray diffraction | A | — | — |
| 5EV4 | Structure IV of intact U2AF65 recognizing the 3' splice site signal | x-ray diffraction | A | — | — |
| 5W0G | Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution | x-ray diffraction | A | ZN, 1PG | — |
| 5W0H | Structure of U2AF65 (U2AF2) RRM2 at 1.11 ångström resolution | x-ray diffraction | A | — | — |
| 6TR0 | Solution structure of U2AF2 RRM1,2 | solution nmr | A | — | — |
| 6TR0 | Solution structure of U2AF2 RRM1,2 | solution nmr | A | — | — |
| 6XLV | Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to adml splice site | x-ray diffraction | A | — | — |
| 6XLW | Crystal structure of U2AF65 bound to adml splice site sequence | x-ray diffraction | A | NA | — |
| 6XLX | Crystal structure of cancer-associated G301D mutant of U2AF65 bound to adml splice site | x-ray diffraction | A | — | — |
| 7S3A | Crystal structure of intact U2AF65 rrm-region bound to adml-C5 oligonucleotide | x-ray diffraction | A | NA | — |
| 7S3B | Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide | x-ray diffraction | A | — | 1 (best 0.67) |
| 7S3B | Crystal structure of intact U2AF65 rrm-region bound to adml-G5 oligonucleotide | x-ray diffraction | A | — | — |
3 records more on the page itself.
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