MolNFT v1 · #113434 · protein
Crystal structure of the LATROPHILIN3 lectin and olfactomedin domains
5AFB · Latrophilin-3: “Crystal structure of the LATROPHILIN3 lectin and olfactomedin domains”. X-ray diffraction, 3 ligands (NAG, NA, CA), 1 pocket (best druggability 0.34). MolNFT v1 #113434 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5AFB
- Type
- protein
- Length
- 347 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Latrophilin-3
- UniProt
- Q80TS3
- Ligands
- NAG, NA, CA
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Latrophilin-3 | protein | 347 | 6% helix, 47% strand | Q80TS3 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- NA · Sodium ion · metal · chains A
- CA · Calcium ion · metal · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.34 | 0.74 | 21 | GOL |
Modifications
Observed in the structure: 5 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 5AFB · Crystal structure of the Latrophilin3 Lectin and Olfactomedin Domains · the same entry in another collection · chain A against A, TM-score 1.00
- Q80TS3 · AlphaFold monomer V2.0 prediction for adhesion G protein-coupled receptor L3 (Q80TS3) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80TS3
- Elsewhere: RCSB PDB 5AFB · PDBe 5AFB · UniProt Q80TS3
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