UniProt Q80TS3
Adhesion G protein-coupled receptor L3 (Q80TS3)
Adhesion G protein-coupled receptor L3 (UniProt Q80TS3): 15 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q80TS3
- Protein
- Adhesion G protein-coupled receptor L3
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 32 · 4 records with a druggable one
Structures
16 records of Q80TS3 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RMK | Crystal structure of the Olfactomedin domain of latrophilin 3 in P65 crystal form | x-ray diffraction | A | — | — |
| 4RMK | Crystal structure of the olfactomedin domain of latrophilin 3 in P65 crystal form | x-ray diffraction | A | — | — |
| 4RML | Crystal structure of the Olfactomedin domain of latrophilin 3 in C2221 crystal form | x-ray diffraction | A | — | — |
| 4RML | Crystal structure of the olfactomedin domain of latrophilin 3 in C2221 crystal form | x-ray diffraction | A | — | — |
| 4YEB | Structural characterization of a synaptic adhesion complex | x-ray diffraction | A | — | — |
| 4YEB | Structural characterization of a synaptic adhesion complex | x-ray diffraction | A | — | — |
| 5AFB | Crystal structure of the LATROPHILIN3 lectin and olfactomedin domains | x-ray diffraction | A | — | — |
| 5FTT | Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR) | x-ray diffraction | C, D, G, H | NAG, NA, CA | — |
| 5FTT | Octameric complex of latrophilin 3 (lec, olf) , UNC5D (ig, IG2, TSP1) and FLRT2 (lrr) | x-ray diffraction | C, D, G, H | — | — |
| 5FTU | Tetrameric complex of Latrophilin 3, Unc5D and FLRT2 | x-ray diffraction | C, D, G, H, K, L | NAG, NA, CA | 19 (best 0.84) |
| 5FTU | Tetrameric complex of latrophilin 3, UNC5D and FLRT2 | x-ray diffraction | C, D, G, H, K, L | — | — |
| 6JBU | High resolution crystal structure of human FLRT3 LRR domain in complex with mouse CIRL3… | x-ray diffraction | A | PO4, NA | 3 (best 0.73) |
| 6JBU | High resolution crystal structure of human FLRT3 lrr domain in complex with mouse CIRL3… | x-ray diffraction | A | PO4, NA | — |
| 7WY5 | ADGRL3/Gq complex | electron microscopy | R | — | 5 (best 0.77) |
| 7X10 | ADGRL3/miniG12 complex | electron microscopy | R | — | 5 (best 0.72) |
| Q80TS3 | AlphaFold monomer V2.0 prediction for adhesion G protein-coupled receptor L3 (Q80TS3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4RMK chain A against the predicted model Q80TS3: TM-score 0.99, RMSD 0.48 Å
- 4RMK chain A against the predicted model Q80TS3: TM-score 0.99, RMSD 0.48 Å
- 5FTT chain H against the predicted model Q80TS3: TM-score 0.99, RMSD 0.59 Å
- 5FTT chain H against the predicted model Q80TS3: TM-score 0.99, RMSD 0.59 Å
- 5AFB chain A against the predicted model Q80TS3: TM-score 0.99, RMSD 0.71 Å
- 6JBU chain A against the predicted model Q80TS3: TM-score 0.99, RMSD 0.76 Å
- 6JBU chain A against the predicted model Q80TS3: TM-score 0.99, RMSD 0.76 Å
- 5FTT chain D against the predicted model Q80TS3: TM-score 0.99, RMSD 0.76 Å
- 5FTT chain D against the predicted model Q80TS3: TM-score 0.99, RMSD 0.76 Å
- 5FTU chain L against the predicted model Q80TS3: TM-score 0.99, RMSD 0.61 Å
Elsewhere
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