MolNFT v1 · #112484 · protein

Crystal structure of human P-cadherin (ss-dimer Q101L)

4ZMP · Cadherin-3: “Crystal structure of human P-cadherin (ss-dimer Q101L)”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.41). MolNFT v1 #112484 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4ZMP
Type: protein
Length: 213 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cadherin-3
UniProt: P22223
Ligands: CA
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cadherin-3	protein	213	3% helix, 44% strand	P22223

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.41	0.80	15	empty

Compared structures

4ZMP · Crystal structure of human P-cadherin (ss-dimer Q101L) · the same entry in another collection · chain A against A, TM-score 1.00
P22223 · AlphaFold monomer V2.0 prediction for cadherin-3 (P22223) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22223
Elsewhere: RCSB PDB 4ZMP · PDBe 4ZMP · UniProt P22223

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