MolNFT v1 · #10802 · protein
Structure of FLIN2, a complex containing the N-terminal lim domain of LMO2 and LDB1-lid
1J2O · Fusion of rhombotin-2 and lim domain-binding protein 1: “Structure of FLIN2, a complex containing the N-terminal lim domain of LMO2 and LDB1-lid”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.33). MolNFT v1 #10802 on…
- PDB
- 1J2O
- Type
- protein
- Length
- 114 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fusion of rhombotin-2 and lim domain-binding protein 1
- UniProt
- P25801, P70662
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.33
Structure
solution nmr · 1 distinct chain · 7% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fusion of rhombotin-2 and lim domain-binding protein 1 | protein | 114 | 7% helix, 15% strand | P25801, P70662 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 67 | 0.33 | 0.76 | 16 | empty |
Compared structures
- 1J2O · Structure of FLIN2, a complex containing the N-terminal LIM domain of LMO2 and ldb1-LID · the same entry in another collection · chain A against A, TM-score 1.00
- P25801 · AlphaFold monomer V2.0 prediction for rhombotin-2 (P25801) · a predicted model of the same protein · chain A against A, TM-score 0.49
- P70662 · AlphaFold monomer V2.0 prediction for lim domain-binding protein 1 (P70662) · a predicted model of the same protein · chain A against A, TM-score 0.31
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25801
- Every structure of UniProt P70662
- Elsewhere: RCSB PDB 1J2O · PDBe 1J2O · UniProt P25801 · UniProt P70662
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