MolNFT v1 · #106239 · protein
Crystal structure of the green fluorescent variant, nowgfp, of the cyan cerulean at pH 9.0
4RTC: “Crystal structure of the green fluorescent variant, nowgfp, of the cyan cerulean at pH 9.0”. X-ray diffraction, 1 ligand (CRF), 2 pockets (best druggability 0.81). MolNFT v1 #106239 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4RTC
- Type
- protein
- Length
- 227 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nowgfp
- Ligands
- CRF
- Pockets
- 2 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 12% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nowgfp | protein | 227 | 12% helix, 52% strand | — |
Ligands and binding sites
- CRF · [(4Z)-2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(1H-indol-3-ylmethylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid · ligand · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.81 | 0.96 | 28 | CRF |
| 2 | 58 | 0.35 | 0.78 | 18 | empty |
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 4RTC · Crystal structure of the green fluorescent variant, nowGFP, of the cyan Cerulean at pH 9.0 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4RTC · PDBe 4RTC
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