MolNFT v1 · #105646 · protein
A regulatory domain of an ion channel
4RAX · Piezo-type mechanosensitive ion channel component 1: “A regulatory domain of an ion channel”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #105646 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4RAX
- Type
- protein
- Length
- 227 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Piezo-type mechanosensitive ion channel component 1
- UniProt
- E2JF22
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Piezo-type mechanosensitive ion channel component 1 | protein | 227 | 22% helix, 38% strand | E2JF22 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 69 | 0.29 | 0.73 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E2JF22
- Elsewhere: RCSB PDB 4RAX · PDBe 4RAX · UniProt E2JF22
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