MolNFT v1 · #105226 · protein
Crystal structure of the human BRPF1 bromodomain in complex with a histone H4K12AC peptide
4QYD · Peregrin: “Crystal structure of the human BRPF1 bromodomain in complex with a histone H4K12AC peptide”. X-ray diffraction. MolNFT v1 #105226 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4QYD
- Type
- protein
- Length
- 122 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peregrin; Histone H4
- UniProt
- P55201, P62805
Structure
x-ray diffraction · 2 distinct chains · 61% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peregrin | protein | 114 | 66% helix, 0% strand | P55201 |
| B | Histone H4 | protein | 8 | 0% helix, 0% strand | P62805 |
Interfaces
1 interface between chains.
- A–B · 442 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (acetylation).
Compared structures
- 4QYD · Crystal Structure of the human BRPF1 bromodomain in complex with a histone H4K12ac peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P55201 · AlphaFold monomer V2.0 prediction for peregrin (P55201) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P55201
- Every structure of UniProt P62805
- Elsewhere: RCSB PDB 4QYD · PDBe 4QYD · UniProt P55201 · UniProt P62805
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