MolNFT v1 · #104111 · protein

Crystal structure of acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in complex with L-ribulose

4Q0V: “Crystal structure of acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in complex with L-ribulose”. X-ray diffraction, 4 ligands (RUU, QDK, NCO), 3 pockets (best druggability 0.62). MolNFT v1 #104111 on GenesisL1: 3D structure…

PDB: 4Q0V
Type: protein
Length: 249 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-ribose isomerase
EC: 5.3.1.-
UniProt: Q93UQ5
Ligands: RUU, QDK, NCO, CO
Pockets: 3 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	L-ribose isomerase (EC 5.3.1.-)	protein	249	20% helix, 27% strand	Q93UQ5

Ligands and binding sites

RUU · alpha-L-ribulofuranose · ligand · 5 copies · chains A
QDK · L-ribulose · ligand · 2 copies · chains A
NCO · Cobalt hexammine(iii) · ligand · chains A
CO · Cobalt (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	254	0.62	0.81	38	RUU, QDK
2	95	0.34	0.74	17	empty
3	52	0.29	0.75	14	empty

Compared structures

4Q0V · Crystal structure of Acinetobacter sp. DL28 L-ribose isomerase mutant E204Q in complex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q93UQ5
Elsewhere: RCSB PDB 4Q0V · PDBe 4Q0V · UniProt Q93UQ5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.